Cutting-Edge and Time-Honored Strategies for Stereoselective Construction of C–N Bonds in Total Synthesis.

Artur K. Mailyan, John A. Eickhoff, Anastasiia S. Minakova, Zhenhua Gu, Ping Lu, and Armen Zakarian*,

Chem. Rev. 2016, 116, 4441-4557.


Towards the synthesis of nuphar sesquiterpene thioalkaloids: stereodivergent rhodium-catalyzed synthesis of the thiolane subunit.

Ping Lu, Aaron T. Herrmann, , Armen, Zakarian*,

J. Org. Chem. 2015, 80, 7581-7589.


Direct enantioselective conjugate addition of carboxylic acids with chiral lithium amides as traceless auxiliaries.

Ping Lu, Jeffrey J. Jackson, John A. Eickhoff, Armen Zakarian*,

J. Am. Chem. Soc. 2015, 137, 656-659. (JACS most read article, 1 month, highlighted in Synfacts 2015, 11, 415.)


Enantioselective synthesis of (−)-maoecrystal V by enantiodetermining C–H functionalization.

Ping Lu†, Artur Mailyan†, Zhenhua Gu, David M. Guptill, Hengbin Wang, Huw M. L. Davies*, and Armen Zakarian*,

J. Am. Chem. Soc. 2014, 136, 17738-17749. († equal contribution, JACS most read article, 1 month)


Total synthesis of maoecrystal V: Early stage C-H functionalization and lactone formation by radical cyclization.

Ping Lu, Zhenhua Gu, Armen Zakarian*,

J, Am. Chem. Soc. 2013, 135, 14552-14555. (JACS most read article, 1 month and 12 months, highlighted in Synfacts 2013, 9, 1256.)


Intramolecular [2+2] photocyclo-addition reactions as an entry to the 2-oxatricyclo[, 9]nonan-3-one skeleton of lactiflorin.

Ping Lu, Eberhardt Herdtweck, Thorsten Bach*,

Chemistry – An Asian Journal, 2012, 7, 1947-1958.


Total synthesis of (+)-Lactiflorin by an intramolecular [2+2]-photocycloaddition. Angew.

Ping Lu, Thorsten Bach*,

Chem. Int. Ed. 2012, 51, 1261-1264. (Highlighted in Synfacts 2012, 8, 353).


The [2+2]-cycloaddition reaction of bisallenes: A dramatic substituent effect.

Ping Lu, Shengming Ma*,

Chin. J. Chem. 2010, 28, 1600-1606


T. Herrmann, and Armen Zakarian* Total Synthesis of Unsymmetrically Oxidized Nuphar Thioalkaloids via Copper-Catalyzed Thiolane Assembly.

Jacob J. Lacharity∥, Jeremy Fournier∥, Ping Lu, Artur K. Mailyan, Aaron

J. Am. Chem. Soc. 2017, 139, 13272-13275.


Lithium Enolates in the Enantioselective Construction of Tetrasubstituted Carbon Centers wtih Chiral Lithium Amides as Noncovalent Stereodirecting Auxiliaries.

Kai Yu†,  Ping Lu†§,  Jeffrey J. Jackson†∥,  Thuy-Ai D. Nguyen†,  Joseph Alvarado†⊥,  Craig E. Stivala†#,  Yun Ma‡,  Kyle A. Mack‡,  Trevor W. Hayton†,  David B. Collum*‡, and  Armen Zakarian*†

J. Am. Chem. Soc. 2017, 139, 527-533.


I–-catalyzed reaction of 5-methoxyoxazoles with organic iodides—An efficient synthesis of azalactones.

Lianghua Lu, Ping Lu, Shengming Ma*,

J. Org. Chem. 2007, 676-680.



What can a metal catalyst do with allenes? One-step formation of steroid scaffolds from readily available starting materials.

Shengming Ma*, Ping Lu, Lianghua Lu, Hairong Hou, Jiemin Wei, Qiwen He, Zhenhua Gu, Xuefeng Jiang, and Xing Jin,

Angew. Chem. Int. Ed. 2005, 44, 5275-5278.


I–-catalyzed methyl-oxygen bond cleavage in 2-methoxyfurans. An efficient synthesis of butenolides.

Shengming Ma*, Lianghua Lu and Ping Lu, 
J. Org. Chem. 2005, 70, 1063-1065.

Abstract Image


Reaction of [60]fullerene with free radicals generated from active methylene compounds by manganese(III) acetate dehydrate.

Tinghu Zhang, Ping Lu, Fan Wang and Guanwu Wang*, 

Org. Biomol. Chem. 2003, 1, 4403-4407.

Graphical abstract: Reaction of [60]fullerene with free radicals generated from active methylene compounds by manganese(iii) acetate dihydrate